Postoperative ileus

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Alvimopan for postoperative ileus

Purpose. The efficacy, safety, pharmacology, pharmacokinetics, drug–drug interactions, and administration of alvimopan for postoperative ileus are reviewed. Summary. Alvimopan is a selective mopioid receptor antagonist with no central nervous system activity. When orally administered after partial smallor largebowel resection in patients with primary anastomosis, alvimopan shortened the return ...

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Management of postoperative ileus.

Postoperative ileus, a temporary cessation in bowel motility, is a common and significant complication of major surgery. Consequences of postoperative ileus include increased patient discomfort, delayed time to adequate nutrition, prolonged length of stay, and increased cost to the patient and healthcare system. The traditional, multi-modal approach to the resolution of postoperative ileus incl...

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Postoperative Ileus: Pathophysiology and Treatment

Postoperative ileus (POI) is a temporary impairment of gastrointestinal (GI) motility occurring universally after major abdominal surgery (Holte & Kehlet, 2002). For the majority of affected surgical patients, POI is transient, lasting approximately 3 to 5 days (Hotokezaka, et al., 1997). The adverse effects of POI are composed of not only physiologic effects such as reduced bowel function, exa...

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Postoperative Ileus A SPECIAL ARTICLE

13 INTRODUCTION Postoperative ileus (POI) is a very common problem after many surgical procedures, may lead to significant patient morbidity, and is a common reason for gastroenterological consultation. POI may be generally defined as transient inhibition of normal GI motility in the postoperative setting, typically lasting 3-5 days after surgery. Clinical consequences of POI include worsened p...

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Risk factors for postoperative ileus

PURPOSE This study aimed to examine extended postoperative ileus and its risk factors in patients who have undergone abdominal surgery, and discuss the techniques of prevention and management thereof the light of related risk factors connected with our study. METHODS This prospective study involved 103 patients who had undergone abdominal surgery. The effects of age, gender, diagnosis, surgic...

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ژورنال

عنوان ژورنال: Journal of Medical and Scientific Research

سال: 2013

ISSN: 2321-1326,2394-112X

DOI: 10.17727/jmsr.2013/1-023